FOSTERING Hope and Healing in the lives of children with PVS
PVS is a serious disease, resulting from a blockage in the blood vessels responsible for blood flow from the lungs back to the heart. Although rare and often life threatening, Lady Josephine Foundation believes that PVS is shifting from a terminal diagnosis to a chronic disease through brave families, caring doctors, and specific research. Josephine’s life with PVS has helped pave a path of hope and potential for these children!
The Lady Josephine Foundation is on a mission to establish and acknowledge our fight for answers that seemed unattainable, to celebrate our victories in a life that has defied the odds, and to support the many people that have & will continue to pursue a treatment plan to better the lives of children with PVS.
“Pulmonary Vein Stenosis (PVS) is a rare disease with a prevalence of around
1.7 cases per 100,000 children under 2 years old.”
“The improvement in surgical repair of PVS and newer stent technology mixed with aggressive
re-intervention has changed the trajectory for these patients tremendously, but with mortality rates
of 30–40% still predicted at 5 years post intervention, more still needs to be done.”
Citation: McLennan DI, Solano ECR, Handler SS, Lincoln J, Mitchell ME and Kirkpatrick EC (2021)
Pulmonary Vein Stenosis: Moving From Past Pessimism to Future Optimism. Front. Pediatr. 9:747812. doi: 10.3389/fped.2021.747812